CEO & Managing Director


  • Founded Foresite Capital in 2011.
  • Co-founded GelTex, which was acquired for $1.6 billion by Sanofi-Genzyme.
  • Co-founded Theravance, Inc., (Total Market Cap of $2.68B) which subsequently changed its name to Innoviva, Inc. (NASDAQ: INVA) and with its spin-off Theravance BioPharma, Inc. (NASDAQ: TBPH), the companies have a combined market capitalization of $2.68 billion.
  • Earned BS and BSEE from Yale University in Applied Math and Computer Science and M.S. from MIT, MD and MBA from Harvard University.
  • Member of Yale’s University Council and the advisory committee of the Yale School of Engineering & Applied Science.
  • 2015, 2016, 2017 Midas list

Jim is the founder of Foresite Capital and an industry leader with 25 years of healthcare entrepreneurial and investing experience. Jim focuses on strategic, operational and financial opportunities to build franchise healthcare businesses. He has been the chief architect of Foresite Capital’s investment organization structure and investment strategy and has played a significant role in numerous Foresite Capital portfolio companies.

Prior to founding Foresite Capital, Jim co-founded two leading biopharmaceutical companies and two healthcare investment practices. While finishing Harvard University  Medical and Business Schools and earning an MS from the Massachusetts Institute of Technology (MIT), he founded GelTex Pharmaceuticals (NASDAQ:GENZ), which brought two drugs to market for less than $80 million. GelTex was acquired in 1998 for $1.6 billion, when its lead drug, Renagel (Renzela) had an annual revenue run rate in excess of $200 million. Today, Renzela is estimated to produce close to $1 billion in annual revenue, 22 years after its launch. Jim also co-founded and was CEO of Theravance, Inc. who share GSK’s respiratory franchise through a joint venture, Innoviva (NASDAQ: INVA), and completed a spin-off, Theravance Biopharma, Inc. (NASDAQ: TBPH).  The two companies have a combined market capitalization of approximately $3.2 billion.

Jim’s investment experience includes being a founding partner of Prospect Venture Partners II and III, and earlier in his career,  a partner at Sierra Ventures, where he helped establish its healthcare services investment practice. Jim has led numerous investments, including Amira Pharmaceuticals (acquired by NYSE: BMS), Amerigroup (NASDAQ: AMGP), Healtheon (NASDAQ:WBMD), and Jazz Pharmaceuticals (NASDAQ: JAZZ).  Jim founded Foresite Capital with the vision of marrying elements of all aspects of his career to create a novel investment platform.

Jim graduated with a B.S. and B.S.E.E. from Yale University, an M.D. from Harvard Medical School, an M.S. from MIT and an M.B.A from Harvard Business School. He has served on the advisory boards and visiting committees to the Harvard-MIT HST program and on Yale’s President Advisory Counsel.